Tinnitus Talk, “a podcast on all things tinnitus,” interviewed Thanos Tzounopoulos, PhD, director of the Pittsburgh Hearing Research Center on his research on developing a drug to treat tinnitus.
Thanos Tzounopoulos, PhD
His work builds on the previously somewhat successful off-label tinnitus drug Retigabine (Trobalt). That drug was taken off the market due to severe side effects. Thanos is now attempting to re-develop it, without the side effects, and better targeted at the source of the neural hyperactivity perceived as tinnitus.
In this episode, we speak extensively about Thanos’ theory of how tinnitus is generated in the brain and the role of (broken) potassium channels in this. He explains all the trial and error that went into re-developing the drug and speaks about the upcoming phases of research needed before the drug can come to market.
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Eye & Ear Foundation of Pittsburgh Grant Policy A grant for research by the Eye & Ear Foundation to the University of Pittsburgh through its Office of Sponsored Programs cannot be used to pay any indirect costs.
