Category: Tinnitus

Reviving Retigabine for Tinnitus Podcast

Thanos Tzounopoulos, PhD

Tinnitus Talk, “a podcast on all things tinnitus,” interviewed Thanos Tzounopoulos, PhD, director of the Pittsburgh Hearing Research Center on his research on developing a drug to treat tinnitus. His work builds on the previously somewhat successful off-label tinnitus drug Retigabine (Trobalt). That drug was taken off the market due to severe side effects. Thanos is now attempting to re-develop it, without the side effects, and better targeted at the source of the neural hyperactivity perceived as tinnitus. In this episode, we speak extensively about Thanos’ theory of how tinnitus is generated in the brain and the role of (broken)

A Window to the Brain: Understanding How What We Hear Influences How We Behave

Ross Williamson, PhD

As humans, our senses, such as hearing, influence how we perceive and recognize the world around us. For example, most everyone has experienced the phenomenon of hearing a certain song and instantly being transported to a specific memory of their life. Researchers in the Department of Otolaryngology, however, are now trying to determine how what we hear can also influence how we behave. How Can Hearing Affect Our Behavior? “Our ability to make decisions based on changes in the auditory environment often involves the accumulation of sensory evidence, where newly acquired information is used to update existing beliefs and drive

Developing a Cure for Tinnitus

Developing A Cure for Tinnitus - Thanos Tzounopoulos, PhD

The Eye & Ear Foundation collects support from donors like you to help propel research forward. Whether big or small, our donors’ gifts make a difference in the lives of patients and their families. One of our favorite stories that exemplifies the impact of continuous support in a given area of research is the story of how the Eye & Ear Foundation provided seed funding to Thanos Tzounopoulos, PhD and the team at the University of Pittsburgh which includes Peter Wipf, PhD, Distinguished Professor in the Department of Chemistry. This funding helped to secure larger grants from the National Institutes

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