Category: Eye Disorders

Immunology and Viral Eye Diseases

Various viruses from the Herpesviridae family seen using an electron micrograph.

When thinking of eye diseases, most people will immediately think of things such as macular degeneration, glaucoma, and diabetic retinopathy. However, many other viral diseases of the eye affect millions of patients around the world. Clinicians and scientists in the Department of Ophthalmology at the University of Pittsburgh School of Medicine are working together to not only treat these diseases but use basic science research to lay the groundwork for future therapies. Diseases of the ocular surface (cornea and conjunctiva) can severely affect eyesight and quality of life and include: Allergies Chemical Burns Microbial Infections Dry Eye Disease The Herpesviridae

Choroid: Unsung Workhorse of the Eye

Jay Chhablani, MD

An often understated yet critically important part of the eye is the choroid. Understanding what the choroid is and its role in vision can one day help researchers and clinicians better diagnose and treat commonly known diseases of the eye, such as macular degeneration. What is the Choroid? The choroid is the most vascular layer of the eye. It supplies nutritional support to photoreceptors (the most critical cells in the retina) and plays a vital role in vision. Its function is very well established in vision-threatening diseases such as age-related macular degeneration, central serous chorioretinopathy, and pachychoroid diseases. However, understanding

Using Our Own Bacteria to Treat Eye Disorders

Eye Disorders

While some people associate the word ‘bacteria’ with disease or infection, Anthony St. Leger, PhD is seeing it in a different light: as a means to better eye treatment. Dr. St. Leger and his team have been investigating how the eye microbiome, a collection of microbes such as fungi, bacteria, and viruses, work together with the immune system to keep your eye healthy. “What we found is that bacteria live on your eye. And those bacteria actually stimulate an immune response that protects the eye from infection,” stated Dr. St. Leger. “We also know that bacteria stay on the eye